Fortunately MobileIron allows you to send messages to users devices using Apple's Notification Center. These messages can be used to inform users that they need to update an application.
The user will be aware that there is an update when they open the Apps@Work application;
|MobileIron: Apps@Work (Showing an Update)|
|MobileIron: Updated Application Details|
|MobileIron: App Update Dialog|
|iOS: Updating An Application|